Same Day PGD screening with only 3 probes for the most common chromosomal aberrations in newborns (X,Y, 21).

Limiting screening to only 3 probes greatly reduces the rate of errors. The choice of chromosomes covers vast majority of those errors which are compatible with life. They represent cases where the patient would face the most difficulties deciding whether to abort, because possible presentations of abnormalities vary from very mild to severe. 

Same Day PGD has the following advantages:

1. Biopsy, FISH and Transfer are all performed on day 3  

The entire FISH process, including analysis and reporting can be accomplished within about 4 hours. Transfer on the day of the biopsy allows avoiding extended culture that some otherwise viable embryos would not survive. This is particularly relevant in cases with few embryos.

2. The entire process is accomplished on site 

Having the entire process under one roof or better still a single directorship creates multiple benefits. The main benefit is an opportunity to repeat the biopsy if FISH laboratory reports that nucleus is missing or fixation is less the optimal.